Scientific Publications


To keep this pipeline full, Noven's research and development teams evaluate and screen hundreds of compounds each year to identify drug candidates that are suitable for transdermal or transmucosal delivery. Principal research areas include central nervous system disorders, female sexual dysfunction and hormone therapy.

Noven's development efforts include feasibility, pre-clinical and clinical studies that constitute some of the most advanced transdermal research being undertaken today. Frequently, the results of these and others studies are published or otherwise presented at leading scientific conferences around the world. New study results and scientific papers that relate to Noven products will be included below as they are made publicly available.

Each article is saved as a printable Adobe Acrobat Reader PDF file. You must have Adobe Acrobat Reader installed on your computer to read these files. If you do not have Reader, you can download a free version here.

In-Vitro Comparison of Excipients for the Permeation Enhancement of Diclofenac Potassium
35th Annual Meeting & Exposition of the Controlled Release Society
(July 2008)

The Use of Acrylic PSA Concentration, Permeation Enhancement and Backing Material Selection to Control the Drug Delivery of a Benzothiazole in Transdermal Drug Delivery Systems
AAPS Annual Meeting
(October 2006)

In-Vitro Transdermal Delivery of Phentermine
AAPS Annual Meeting
(October 2006)

Transdermal Drug Delivery of Polar Derivatives of Ketoprofen Free Acid Through Human Cadaver Skin
AAP Annual Meeting
(October 2006)

The Effect of Primary and Secondary Packaging Materials on the Stability of Drug-In-Adhesive Transdermal Drug Delivery Systems
AAPS Annual Meeting
(October 2006)

Innovations in Passive Transdermal Drug Delivery – High Doses in a Small Patch
A –CRS 2006 Annual Meeting
(July 2006)

Transdermal Delivery of the Antiangiogenic
Compound 2-methoxyestradiol

33rd Annual Meeting & Exposition of the Controlled Release Society
(July 2006)

In-vitro Transdermal Permeation Comparison
of Sufentanil vs. Fentanyl

AAPS Annual Meeting
(November 2005)

Transdermal Drug Delivery of Ketoprofen Esters
Through Human Cadaver Skin

AAPS Annual Meeting
(November 2005)

In-vitro Permeation Enhancement of Benzothiazole from Transdermal Drug Delivery Systems Utilizing Fatty Acid Derivatives
AAPS Annual Meeting
(November 2005)

In-vitro Transdermal Delivery of Fludrocortisone
AAPS Annual Meeting
(November 2005)

Transdermals: Yesterday, Today, and Tomorrow
Releasing Technology Workshop presented at the
Controlled Release Society 2005 Annual Meeting

(June 2005)

Materials Relating to Fentanyl Patch Citizen Petitions
(January 2005)

In-Vitro Permeation and Delivery Profile from Transdermal Drug Delivery System Utilizing Varying Ratios of Hard and Soft Monomers Comprising Acrylic Adhesives
(November 2004)

Enhanced Transdermal Permeation Performance
Utilizing Pro-drugs of Testosterone

(November 2004)

Acrylic Polymer Backing Films for Controlling In-Vitro Permeation and Delivery Profile of Estradiol from Transdermal Drug Delivery Systems
(November 2004)

Effect of Backing Materials on Clonidine
Transdermal Drug Delivery

(November 2004)

Release Profile of Transdermal Drug Delivery System
Utilizing Clonidine Crystals of Varying Particle Size

(November 2004)

Transdermal Permeation of Fentanyl
from Silicone Pressure Sensitive Adhesive Blends

(July 2003)

CombiPatch® Significantly Improves Women's Sexual Quality of Life Compared to Prempro in
(April 2003)

Renin Substrate Levels Decrease With Transdermal Hormone Therapy
and Increase With Oral Hormone Therapy
(April 2003)

In-Vitro Transdermal Permeation Performance of Drug and Pro-drug Combinations
(November 2002)

In-Vitro Permeation of Low Molecular Weight Amine Drugs in Transdermal Drug Delivery Systems
(November 2002)

Kinetic Study of Threo-Methylphenidate Degradation Reaction to Erythro Isomer in MethyPatch Transdermal System
(November 2002)

In-Vitro to In-Vivo Evaluation for Scopolamine Transdermal Delivery
(November 2002)

Serum Endocrine Markers and Psychosexual Mood in Postmenopausal Women: The Difference Between Transdermal and Oral HRT
Presentation by Dr. Subir Roy at the 10th World Congress on the Menopause
(June 2002)

Comparison of Dissolution Apparatus for Testing of Transdermal Systems
(October 2001)

An in-vitro Permeation Model to Evaluate Various Benzocaine Transoral Formulations
(October 2001)

Innovative Technology for Menopause
Abstract of "Size Matters" presentation made at the 3rd Amsterdam Menopause Symposium.
(September 2001)

Developments in Transdermal Technology (August 2001)

In-Vitro/In-Vivo Correlation (IVIVC) of Transdermal Estradiol Systems (October 30-31, 2000)

In-Vitro Permeation of Azelastine Transdermal Delivery Devices (October 31, 2000)

Permeation of Cyclobenzaprine from Transdermal Delivery Devices Through Human Cadaver Skin (October 31, 2000)

Photostability Testing of Transdermal Systems (October 31, 2000)

Utilizing Ethyl Cellulose to Sustain the Delivery of Hormones Through Skin over Seven Days (October 31, 2000)

The Study of Transdermal Administration of Ace Inhibitors and Improved Absorption of their Prodrugs (November 2, 2000)

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